IMPROVEMENT OF DIFFERENTIAL DIAGNOSTICS OF SMALL PELVIC INFLAMMATORY DISEASE
SEVERITY IN WOMEN OF CHILDBEARING AGE 

Biryuchkova Ol'ga Aleksandrovna, Obstetrician-gynecologist, Penza regional pediatric clinical hospital named after N. F. Filatov (43 Bekeshskaya street, Penza Russia), iolgabox@yahoo.com
Vinogradova Ol'ga Pavlovna, Doctor of medical sciences, professor, sub-department of obstetrics and gynecology, branch of Russian Medical Academy of Continuous Vocational Education (8A Stasova street, Penza, Russia), o_vinogradova69@mail.ru
Shtakh Aleksandr Filippovich, Candidate of medical sciences, head of sub-department of obstetrics and gynecology, Medical Institute, Penza, State University (40 Krasnaya street, Penza, Russia), alexstach@mail.ru

618.13-07

10.21685/2072-3032-2017-1-6

Background. The aim of the work is to improve differential diagnostics of the small pelvic inflammatory disease severity degree.
Materials and methods. The authors examined 40 women, who formed a control group of donors, 90 patients with small pelvic inflammatory diseases (SPID). The laboratory research included an analysis of organism’s system inflammatory response by estimating ultra C-reactive protein, fibrinogen, D-dimer and Fibrin monomers soluble complex in the serum.
Results. There is a direct correlation between the disease severity and the values of the estimated blood markers.
Conclusions. When determining the disease severity degree the following indicators are of diagnostic significance: levels of D-dimer – for mild cases from 83,5 to 159,5 ng/ml; for middle cases – from 159,6 to 418 ng/ml, and for severe cases – over 419 ng/ml; Fibrin monomers soluble complex – for mild cases – up to 3,525 mg/100ml; for middle cases - from 3,526 to 5,25 mg/100ml; for severe cases – over 5,26mg/100ml ; fibrinogen – for mild cases – up to 3,15 g/l; for middle cases – from 3,16 to 4,15 g/l; for severe cases – over 4,16g/l; ultra C-reactive protein – for mild cases – from 0,775 to 1,98 mg/l; for middle cases – from 1,99 mg/l to 3,56 mg/l; for severe cases - over 3,56 mg/l.

Pelvic inflammatory disease (PID); system of hemostasis; markers of inflammation; inflammation degree criteria.

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